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Treatment Overview.

Targeted therapy is a type of cancer treatment that uses drugs designed to "target" cancer cells without affecting normal cells.

Cancer cells typically have changes in their genes that make them different from normal cells. Genes are part of a cell's DNA that tell the cell to do certain things. When a cell has certain gene changes, it doesn't behave like a normal cell. For example, gene changes in cancer cells might allow the cell to grow and divide very quickly. These types of changes are what make it a cancer cell.

But there are many different types of cancer, and not all cancer cells are the same. For example, colon cancer and breast cancer cells have different gene changes that help them grow and/or spread. Even among different people with the same general type of cancer (such as colon cancer), the cancer cells can have different gene changes, making one person's specific type of colon cancer different from another person's.

Eligibility For Treatment.

How often and how long you receive targeted therapy depends on:

  • Your type of cancer and how advanced it is
  • The type of targeted therapy
  • How your body reacts to treatment

You may have treatment every day, every week, or every month. Some targeted therapies are given in cycles. A cycle is a period of treatment followed by a period of rest. The rest period gives your body a chance to recover and build new healthy cells.

Preparation Before Treatment.

Target Therapies are often given by-

  • Small-molecule drugs are pills or capsules that you can swallow.

  • Monoclonal antibodies are usually given through a needle in a blood vein. Hence, not many preparations need to be done.

About Treatment.

Once a candidate target has been identified, the next step is to develop a therapy that affects the target in a way that interferes with its ability to promote cancer cell growth or survival. For example, a targeted therapy could reduce the activity of the target or prevent it from binding to a receptor that it normally activates, among other possible mechanisms. 

Most targeted therapies are either small molecules or monoclonal antibodies. Small-molecule compounds are typically developed for targets that are located inside the cell because such agents are able to enter cells relatively easily. Monoclonal antibodies are relatively large and generally cannot enter cells, so they are used only for targets that are outside cells or on the cell surface.

Post-Treatment Care Treatment.

You may receive targeted therapy depending on:

  • Your type of cancer and how advanced it is
  • The type of targeted therapy
  • How your body reacts to treatment

You may have treatment every day, every week, or every month. Some targeted therapies are given in cycles. A cycle is a period of treatment followed by a period of rest. The rest period gives your body a chance to recover and build new healthy cells.

Treatment Recovery Tips.

Targeted therapy affects people in different ways. How you feel depends on how healthy you are before treatment, your type of cancer, how advanced it is, the kind of targeted therapy you are getting, and the dose. Doctors and nurses cannot know for certain how you will feel during treatment.

Treatment FAQs.

What are the side effects of targeted therapy?

The most common side effects of targeted therapy include diarrhea and liver problems. Other side effects might include problems with blood clotting and wound healing, high blood pressure, fatigue, mouth sores, nail changes, the loss of hair color, and skin problems. Skin problems might include rash or dry skin. Very rarely, a hole might form through the wall of the esophagus, stomach, small intestine, large bowel, rectum, or gallbladder.

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